research Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
Sox9 is crucial for hair follicle stem cells to become melanocytes instead of glial cells.
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research Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential
The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
research Gene expression profiling gets to the root of human hair follicle stem cells
Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
research Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research From neural crest cells to melanocytes: cellular plasticity during development and beyond
Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
research Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo
New mouse models help study melanocytic cells for melanoma research.
research Loss of ‘Epidermal Melanin Unit’ Integrity in Human Skin During Melanoma-Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Stem cell dynamics in the hair follicle niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research Hardwiring Stem Cell Communication through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research Expression patterns of MITF during human cutaneous embryogenesis: evidence for bulge epithelial expression and persistence of dermal melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Stabilization of β-catenin promotes melanocyte specification at the expense of the Schwann cell lineage
Activating β-catenin increases melanocytes and decreases Schwann cells.
research Skin melanocytes: biology and development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Heterogeneity of neural crest-derived melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research Biology of melanocytes in mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
research Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation
Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
research Melanocytes: The new Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
research A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling
EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
research Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research Keratinocyte Stem Cells but Not Melanocyte Stem Cells Are the Primary Target for Radiation-Induced Hair Graying
Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
research Wnt10b Promotes Differentiation of Mouse Hair Follicle Melanocytes
Wnt10b helps hair follicle cells mature and produce pigment.
research Regulation of melanocyte stem cell behavior by the niche microenvironment
The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
research A rare repigmentation pattern in a vitiligo patient: a clue to an epidermal stem-cell reservoir of melanocytes?
Repigmentation in vitiligo may come from melanocyte stem cells in the skin.
research Stress-sensing in the human greying hair follicle: Ataxia Telangiectasia Mutated (ATM) depletion in hair bulb melanocytes in canities-prone scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research The melanocyte photosensory system in the human skin
Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
research Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice
Only skin melanocytes, not other types, can color hair in mice.
research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle
A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
research Immunohistopathological analysis of frizzled-4-positive immature melanocytes from hair follicles of patients with Rhododenol-induced leukoderma
Rhododendrol in skin-whitening products can cause skin depigmentation and immune reactions.
research Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment
The technique can isolate cells to help treat skin pigmentation issues.