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research 708 Polycomb-mediated repression and Sonic hedgehog signaling regulate Merkel cell specification

April 2016 in “Journal of Investigative Dermatology”

Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

H3K9me3 Controls Epidermis Morphogenesis by Regulating RNA Polymerase II Dynamics at Developmental Promoters and Enhancers

research H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers

May 2026 in “Nature Communications”

H3K9me3 is crucial for proper skin development and structure.

research Stem Cells and their Niches

1 citations , January 2013 in “Journal of Investigative Dermatology”

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression

research 764 DNA dioxygenases Tet1/2/3 control hair matrix keratinocyte differentiation and hair shaft shape via regulation of hair keratin gene expression

June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.