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5 / 801 resultslearn Stem Cell Factor
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn nonspecific group of glycoproteins
learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
Research
5 / 1000+ resultsresearch Circulating monocytes as a marker of response to adalimumab in patients with hidradenitis suppurativa: A single institution, real-world cohort study
Higher monocyte counts may predict poor response to adalimumab in hidradenitis suppurativa patients.
research Circulating monocytes as a marker of response to adalimumab in patients with hidradenitis suppurativa
This retrospective study of 143 patients with hidradenitis suppurativa (HS) treated with adalimumab found that baseline monocyte counts can predict treatment effectiveness. Patients with monocyte counts \(\geq\) 925/\(\mu\)l had a significantly higher risk of adalimumab ineffectiveness, with a hazard ratio of 5.87. Drug survival rates at 12 and 24 months were significantly higher in patients with lower monocyte counts, at 95.7% and 90.6%, compared to 61.5% and 52.7% in those with higher counts. The optimal monocyte count cut-off for predicting response was \(\geq\) 925/\(\mu\)l, with a specificity of 90.5% and sensitivity of 46.2%. Other factors like age, BMI, and HS severity did not significantly affect treatment outcomes.
research The Use of New Hematological Markers in the Diagnosis of Alopecia Areata
Certain blood markers, especially MLR, can help diagnose alopecia areata.
research Retrospective Comparison of Inflammatory Markers in Severe Acne Vulgaris Patients and Normal Population
Severe acne patients have higher inflammatory markers than healthy people.
research PA30 Evaluation of markers of inflammation and oxidative stress in patients with premature canities
Premature canities is linked to low vitamin D and B12, family history, and higher MHR.
Community Join
5 / 1000+ resultscommunity I got my bloodwork done... What now?
The user has been experiencing hair thinning despite taking finasteride and minoxidil for six months. Bloodwork suggests a vitamin D deficiency, and users recommend consulting a doctor and possibly supplementing vitamin D.
community MCL1 does anyone knows anthying about it
MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.
community What blood markers to get tested before starting any 5-AR inhibitor?
The conversation is about which blood markers to test before starting a 5-AR inhibitor for hair loss. The user mentions already testing Total T, Free T, SHBG, Estradiol, Haematocrit, Red blood cell count, and White cell count, and asks if DHT or additional markers are needed.
community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.
Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.
community Mystery compound found to be safe and effective at treating hair loss. Details in comments.
A compound called MTP3 from the Monoterpene family was found to be safe and highly effective at treating hair loss by inhibiting the FGF5 gene, but its identity is undisclosed for commercial reasons. No specific treatments like Minoxidil, finasteride, or RU58841 were discussed.