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learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn methylsulfonylmethane
learn multipeptides
Research
5 / 133 resultsresearch Aqueous Extract of Bacopa procumbens and the NAPEL Formulation Mitigate MPTP-Induced Neurotoxicity via Nrf2/HSF1/HIF-1α Signaling in a Parkinson’s Disease Model
Bacopa procumbens extract may help protect the brain in Parkinson's disease.
research The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson’s disease
Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
research Efficacy and safety of tofacitinib therapy in Asian patients with severe alopecia areata
Tofacitinib helps regrow hair in severe alopecia patients, but more research is needed.
research Identical p53 gene mutation in malignant proliferating trichilemmal tumour of the scalp and small cell carcinoma of the common bile duct: the necessity for therapeutic caution?
Identical p53 gene mutations in different cancers suggest the need for careful treatment.
research 272 Structural changes in human skin after topical application of glucocorticoids assessed by in vivo imaging technologies
Topical glucocorticoids thin the skin and change collagen structure.
Community Join
5 / 1000+ resultscommunity Any chemists want to manufacture PP405 / JXL069? (Steps inside)
The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.
community Possible natural pp405 solution
Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.
community 6 months of using Hims finasteride and minoxidil spray!
A user shared their positive 6-month experience using Hims finasteride and minoxidil spray for hair loss, with others discussing the effectiveness and side effects of topical treatments. Instructions on how to use the spray were also provided.
community Hey guys, just wanted to share my hair loss journey! Been taking finasteride 1mg and applying minoxidil once a day for 7 months now. Definitely seeing some progress, my hair looks and feels thicker. Anyone else trying these products? Let me know your experience!
This conversation is about a user sharing their progress with treating hair loss using finasteride and minoxidil, which others responded to with advice on dosage and other treatments such as microneedling. People also discussed the importance of doing research before starting treatment and being prepared for possible side effects.
community 21M with a nasty case of MPB; Heres what's on my radar for the future.
Hopeful treatments for hair loss, including Verteporfin, Androgen Receptor Degradation, and SCUBE3. These treatments offer potential solutions to slow or stop the effects of androgens on the scalp.