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GlossarymRNA expression

process of producing mRNA from a gene's DNA template

mRNA expression, also known as messenger RNA expression, refers to the process by which the information encoded in a gene is used to produce mRNA molecules. These mRNA molecules serve as templates for synthesizing proteins, which perform various functions in the body. Measuring mRNA expression levels can provide insights into how active a particular gene is under certain conditions, which is crucial for understanding biological processes and disease mechanisms, including those related to hair growth and alopecia.

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Research

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research Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene

1 citations , February 2025 in “Journal of Dairy Science”

The SLICK1 allele in Holstein heifers affects hair and immune traits without altering prolactin signaling.

research Cyclosporin inhibits the apoptosis and effects the mRNA expressions of selected growth factors in cultured mouse hair follicles

January 2003 in “Journal of Clinical Dermatology”

Cyclosporin promotes hair growth by boosting cell growth and reducing cell death.

Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome

research Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome

69 citations , September 2006 in “Human Reproduction”

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

research Effect of oleuropein on mRNA and protein expression of growth factors in C57BL/6N mouse skin tissue.

December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)”

Oleuropein increases IGF-1 levels in mouse skin.

Antioxidant Enzyme Expression of mRNA and Protein in the Epididymis of Finasteride-Treated Male Rat Offspring During Postnatal Development

research Antioxidant enzyme expression of mRNA and protein in the epididymis of finasteride-treated male rat offspring during postnatal development

2 citations , September 2017 in “Archives of Medical Science”

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

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Community Join

5 / 51 results

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 24 upvotes 5 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 2 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 3 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

in Finasteride/Dutasteride 37 upvotes 3 years ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

community What an amazing time to be alive

in Finasteride/Dutasteride 187 upvotes 2 years ago

The post discusses a user's experience with hair loss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hair loss solution.

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Learn

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learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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