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GlossaryMT-CO1

encodes a key enzyme subunit for cellular energy production

MT-CO1, also known as Mitochondrially Encoded Cytochrome C Oxidase I, is a gene found in mitochondrial DNA that encodes a key subunit of the enzyme cytochrome c oxidase. This enzyme is crucial for the electron transport chain, which is a series of reactions that produce energy in the form of ATP within cells. Mutations in MT-CO1 can affect cellular energy production and are associated with various mitochondrial disorders.

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Research

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research 1368 Does mitochondrial dysfunction drive immune privilege collapse in lichen planopilaris pathogenesis?

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mitochondrial dysfunction may contribute to chronic inflammation and immune system issues in Lichen planopilaris.

research 811 Mitochondrial MPZL3 in the inner root sheath regulates human hair follicle cycling ex vivo

1 citations , July 2024 in “Journal of Investigative Dermatology”

MPZL3 protein affects hair growth cycles and could help manage hair loss.

research 1433 Epithelially derived, mitochondrial MPZL3 negatively regulates murine and human hair follicle cycling

April 2023 in “Journal of Investigative Dermatology”

A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.

The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles

research 558 The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles

November 2022 in “Journal of Investigative Dermatology”

Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.

Spontaneous Intrinsic Aging in Organ-Cultured Human Skin as a Novel Ex Vivo Assay to Test Anti-Aging Actives

research 581 Spontaneous, Intrinsic Aging in Organ-Cultured Human Skin as Novel Ex Vivo Assay to Test Candidate Anti-Aging Actives

November 2022 in “Journal of Investigative Dermatology”

The document concludes that a new method has been developed to test anti-aging substances on human skin, showing that these substances can reduce skin aging signs.

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