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research National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2

391 citations , September 2015 in “Journal of Clinical Lipidology”

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications

365 citations , March 2021 in “Frontiers in Bioengineering and Biotechnology”

Nanocarriers can improve drug delivery through the skin by overcoming barriers.

Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins

research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.

356 citations , December 1986 in “The journal of cell biology/The Journal of cell biology”

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

research Dual growth factor releasing multi-functional nanofibers for wound healing

355 citations , August 2013 in “Acta Biomaterialia”

The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.

research Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases

263 citations , February 2013 in “Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology”

Polymeric nanoparticles show promise for treating skin diseases.

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community Natural protocol doesn’t work !

in Update 15 upvotes 2 months ago

community Napkin math: are we using 100x more topical finasteride than necessary?

in Finasteride/Dutasteride 4 upvotes 3 months ago

Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.

community Naturally high T (1,100+) causing diffuse thinning while on Dut

in Chat 23 upvotes 4 months ago

A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.

community Do natural remedies actually work or it is nonsense?

in Chat 3 upvotes 4 months ago

Natural remedies may improve hair and scalp health but do not stop hair loss related to DHT or other imbalances. Proven treatments like Minoxidil and Finasteride are recommended for effective results.

community Nanoxidil Is Probably Better Than Minoxidil. Big Pharma Is Why You’ve Never Heard Of It.

in Research/Science 4 months ago

Nanoxidil may be more effective than Minoxidil for hair loss due to better follicle penetration, but it lacks widespread recognition and research because it's owned by a small company and classified as a cosmetic. The pharmaceutical system favors Minoxidil due to its established market presence and profitability, leaving Nanoxidil largely unstudied and unknown.

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