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research Biology of Hair Growth and Influence of External Factors: Ecology, Stress, Nutrition

June 2025 in “Universal library of medical and health sciences.”

The article reviews the biological mechanisms of hair growth and assesses the impact of external factors such as ecology, chronic stress, and nutrition. It highlights how air pollution, UV radiation, and heavy metals can disrupt hair cycle phases and dermal papilla functions. Stress-induced hair loss is linked to HPA axis hyperactivity, neuropeptide signaling, and local inflammation. The study emphasizes the need for a comprehensive, multifactorial approach and nutritional monitoring for personalized hair loss therapy. This research is valuable for specialists in trichology, dermatophysiology, ecotoxicology, and nutrition, aiming to develop strategies to maintain hair follicle homeostasis.

Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish

research Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish

October 2022 in “Frontiers in Endocrinology”

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

research Innervated Biomaterials for Improved Cutaneous Wound Healing: A Review of Recent Advancements and Future Prospects

2 citations , June 2025 in “International Journal of Nanomedicine”

New biomaterials can improve wound healing by promoting nerve and tissue regeneration.

research The Anagen Hair Cycle Induces Systemic Immunosuppression of Contact Hypersensitivity in Mice

19 citations , February 1998 in “Cellular Immunology”

Hair growth phase in mice weakens certain immune responses.

Neuroendocrine, Neurotransmitter, and Gut Microbiota Imbalance Contributing to Potential Psychiatric Disorder Prevalence in PCOS

research Neuroendocrine, Neurotransmitter, and Gut Microbiota Imbalance Contributing to Potential Psychiatric Disorder Prevalence in PCOS

September 2023 in “F&S reports”

PCOS may increase the risk of mental health issues like depression and anxiety.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 76 upvotes 1 year ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Creatine is the opposite of minoxidil !

in Research/Science 320 upvotes 4 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 1 year ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community He used Dutasteride for 20 years. Interview

in Treatment 112 upvotes 1 year ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

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