7 citations
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March 2023 in “Gynecological Endocrinology” After tumor removal, the woman regained normal hormone levels, menstruated, and had a healthy baby.
July 2026 in “Journal of Ovarian Research” This study conducted single-cell RNA sequencing on a 41-year-old woman with ovarian steroid cell tumors-not otherwise specified (SCT-NOS) and hyperandrogenism, identifying seven cell types, including four KRT19⁺ steroidogenic cell subtypes, within the tumor microenvironment. The analysis revealed aberrant gene expression related to ovarian steroidogenesis and steroid biosynthesis pathways, aligning with hyperandrogenism pathobiology. Additionally, five immune cell types were identified, with tumor-associated macrophages and dendritic cells being predominant. The findings provide insights into the cellular heterogeneity and molecular mechanisms of ovarian SCT-NOS, enhancing understanding and encouraging further research into this rare tumor type.
March 2026 in “JCEM Case Reports” Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.
October 2024 in “Journal of the Endocrine Society” Ovarian steroid cell tumors can mimic adrenal hyperplasia, and surgery can normalize hormone levels.
June 2020 in “ACTA MEDICA IRANICA” A rare benign ovarian tumor caused virilization in a postmenopausal woman, treated successfully with surgery.
