Bilateral Ovarian Steroid Cell Tumor in a Postmenopausal Woman with Progressive Hyperandrogenism

March 2026 in “ JCEM Case Reports ”

Maria Sara Tapia Sanchiz, Alicia Justel Enríquez, Rosa Álvarez, Fernando Sebastian-Valles, Mónica Marazuela

hyperandrogenism androgenic alopecia hirsutism testosterone insulin resistance ovarian steroid cell tumor

TLDR Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.

A 71-year-old postmenopausal woman presented with severe hyperandrogenism and progressive hirsutism, characterized by elevated testosterone levels and symptoms such as androgenic alopecia and insulin resistance. Despite normal imaging results for adrenal glands and adnexa, clinical suspicion led to a bilateral adnexectomy, which revealed a bilateral ovarian steroid cell tumor. Post-surgery, the patient's testosterone levels normalized, and her hirsutism improved progressively.

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research Approach to Investigation of Hyperandrogenism in a Postmenopausal Woman

November 2022 in “The Journal of Clinical Endocrinology and Metabolism”

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

research Rare Case of Ovarian Steroid Cell Tumor Not Otherwise Specified in a Postmenopausal Woman

January 2022 in “Journal of Morphological Sciences”

A woman's rare ovarian tumor was treated with surgery, which stopped her symptoms and normalized her hormone levels.

research Ovarian Leydig Cell Tumor and Postmenopausal Hirsutism with Signs of Virilization

4 citations , March 2021 in “Case Reports”

A woman's excessive hair growth and masculine features were due to a rare benign ovarian tumor and endometrial cancer, which improved after surgery.

Semantic ratio: 80%