research Genetic, Hormonal, and Metabolic Aspects of PCOS: An Update
The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
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5 / 1000+ results research Hirsutism Due to Polycystic Ovarian Syndrome: An Integrative Review of Pathophysiology and Management
Combining modern and Unani treatments may offer better care for hirsutism in PCOS.
research Exploring the Therapeutic Potential of Phytochemicals Apigenin and Ellagic Acid in Managing Polycystic Ovarian Syndrome and Its Comorbidities: A Comprehensive Review
Apigenin and ellagic acid may help manage PCOS symptoms.
research In-Silico Screening of Potential Anti-Androgenic and Anti-Estrogenic Phytocompounds from Saraca Asoca for Polycystic Ovary Syndrome Treatment
This study investigates the potential of phytocompounds from Saraca asoca for treating polycystic ovary syndrome (PCOS) by targeting the ovarian steroidogenesis pathway. Using in-silico methods, 56 ligands were analyzed for their binding affinity to key enzymes and receptors involved in hormone production. Procyanidin B2 and leucopelargonidin showed the highest docking scores, indicating strong potential as inhibitors of aromatase and 17-HSD1, which are involved in estrogen and testosterone biosynthesis. The top seven compounds, including procyanidin B2 and leucopelargonidin, met drug-likeness criteria and demonstrated favorable chemical and biological reactivity, suggesting their promise as treatments for hormonal imbalance in PCOS.
research Steroidogenesis in Steroid-Related Cancers
Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
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5 / 18 resultscommunity 11-month update. This time wet hair comparison!
The post discusses an 11-month hair loss treatment journey using dutasteride, minoxidil, nizoral, and 1.5mm derma rolling. The responses inquire about the frequency of derma rolling and express optimism for further progress.
community 24 y/o woman diagnosed with AGA today. Scared and confused.
A 24-year-old woman being diagnosed with androgenic alopecia (AGA) who is scared and confused about her hair loss, and the treatment options of Minoxidil, finasteride, RU58841, spironolactone, and possibly a biopsy.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
by
nkrata
in Research
830 upvotes
1 year ago Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community My scalp punch biopsy results🤔?
Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.
community Low-Dose Oral Minoxidil Does Not Significantly Affect BP
Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.