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acid used for antimicrobial, anti-inflammatory and anti-androgenic properties
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natural substance from Neem tree with medicinal and pesticidal properties
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5 / 1000+ resultsresearch A Stability Indicating UPLC Method for Finasteride and Its Related Impurities
A new method effectively analyzes Finasteride and its impurities, even under stress conditions.
research RP-HPLC-Based Stability-Indicating Analytical Method for Concurrent Determination of Finasteride and Tadalafil: Development and Validation
A reliable method was developed to measure Finasteride and Tadalafil together, showing they degrade under certain conditions.
research Effect of Alpha Lipoic Acid on Smoking-Induced Skin Damage
Alpha Lipoic Acid helps protect skin from smoking damage.
research 15-Hydroxyprostaglandin Dehydrogenase Inhibitor Restores Endothelial Function Under Dihydrotestosterone-Induced Stress in Human Dermal Microvascular Endothelial Cells
This study explores the effects of dihydroisoquinolinone piperidinylcarboxy pyrazolopyridine (DPP), a 15-hydroxyprostaglandin dehydrogenase inhibitor, on human dermal microvascular endothelial cells (HDMECs) under dihydrotestosterone (DHT)-induced stress, a factor in androgenetic alopecia. DPP significantly reduced oxidative stress by lowering reactive oxygen species (ROS) levels, restored mitochondrial function, and increased ATP production. It also improved endothelial cell migration and tube formation, essential for perifollicular vascularization. DPP mitigated stress-related MAPK pathway signaling, suggesting restored endothelial homeostasis. These findings indicate that DPP may support hair follicle regeneration by preserving endothelial function under DHT-induced conditions, offering potential as a complementary treatment for hair loss. Further in vivo studies are needed to confirm its role in hair follicle regeneration.
research Oxidative Modification in Human Hair: The Effect of the Levels of Cu (II) Ions, UV Exposure and Hair Pigmentation
Reducing copper (II) ion levels in hair can decrease hair damage.
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5 / 111 resultscommunity Could fatty liver(other issues related to it..)play a role in Dupa/Aga?
Fatty liver and related issues may influence hair loss conditions like Dupa/Aga. Treatments discussed include Minoxidil, finasteride, RU58841, myo-inositol, and L-glutamine.
community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders
Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Is 2-deoxy-D-ribose (2dDR) good for human hair?
Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).
community Why don’t more people use hair fibers?
Hair fibers can effectively cover thinning hair when used with minoxidil and hairspray but require daily application and can be inconvenient in certain conditions. Some users prefer treatments like finasteride, dutasteride, microneedling, or wigs due to the maintenance and limitations of hair fibers.