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Fibrous Papule of the Face, Similar to Tuberous Sclerosis Complex-Associated Angiofibroma, Shows Activation of the Mammalian Target of Rapamycin Pathway: Evidence for a Novel Therapeutic Strategy?

research Fibrous Papule of the Face, Similar to Tuberous Sclerosis Complex-Associated Angiofibroma, Shows Activation of the Mammalian Target of Rapamycin Pathway: Evidence for a Novel Therapeutic Strategy?

12 citations , February 2014 in “PLoS ONE”

Topical rapamycin may effectively treat fibrous papules on the face.

research Differential expression of mTOR signaling pathway proteins in lichen planopilaris and frontal fibrosing alopecia

5 citations , September 2018 in “Acta histochemica”

The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.

The Role of P-Cadherin in Skin Biology and Pathology: Lessons from the Hair Follicle

research The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle

15 citations , February 2015 in “Cell & tissue research/Cell and tissue research”

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

research Phytochemical and Therapeutic Evaluation of Curcumin and Piperine in Alopecia

July 2026 in “International Journal of Drug Delivery Technology”

Curcumin and piperine may effectively and safely promote hair regrowth in alopecia.

research Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930

65 citations , February 2011 in “Molecular cancer therapeutics”

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

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community P-1075: a BETTER version of Minoxidil

in Research/Science 9 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community Topical finasteride (P-3074) inhibits scalp DHT up to 70%

in Finasteride/Dutasteride 20 upvotes 5 months ago

Topical finasteride (P-3074) can inhibit scalp DHT by up to 70%, with some users experiencing systemic absorption similar to oral use. Users discuss varying application frequencies and concentrations, with some noticing side effects when overused.

community How does Pedro P have a full head of hear. I'm losing mine and will be bald within 1 year. I'm not even 30yo.

in Chat 640 upvotes 9 months ago

Pedro Pascal's full head of hair is likely due to genetics, finasteride, and possibly hair transplants. Many actors use finasteride to maintain their hair.

community Still losing on fin 5x & dut 2x p/w (1.5 years in) - next steps advice

in Finasteride/Dutasteride 1 upvotes 1 year ago

The user has been using finasteride and minoxidil for 5 years with initial success but is now experiencing hair thinning despite increasing dutasteride usage. They are considering adjusting dutasteride frequency and possibly adding treatments like eucapil, minoxidil, and GHK-Cu peptides.

community On the topic of HMI-115 and prolactin: has anyone tried adding Vitamin B6 (P-5-P) to their topical solutions?

in Research/Science 7 upvotes 2 years ago

The conversation discusses the potential benefits of adding Vitamin B6 (P-5-P) to topical hair loss treatments like RU58841, finasteride, or minoxidil. The user suggests that Vitamin B6 might enhance these treatments by naturally lowering scalp prolactin.

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learn Transcutol P

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