research Severe Hair Loss of the Scalp due to a Hair Dye Containing Para phenylenediamine 20 citations , June 2011 in “ISRN Dermatology (Print)” A woman lost most of her hair due to an allergic reaction to a hair dye ingredient.
research Chemical Leukoderma from Hair Dye Containing para-Phenylenediamine 9 citations , July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
research Implication of microRNA regulation in para-phenylenediamine-induced cell death and senescence in normal human hair dermal papilla cells 8 citations , March 2015 in “Molecular Medicine Reports” Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.
research Patch tests with commercial hair dye products in patients with allergic contact dermatitis to para-phenylenediamine 6 citations , January 2016 in “Indian Journal of Dermatology Venereology and Leprology” Most hair dyes can cause allergic reactions, so test before use.
research Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes 1 citations , October 2025 in “Iranian journal of pharmaceutical research” Geranyl acetate can protect skin cells from damage and inflammation caused by para-phenylenediamine.