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Did you mean Pegylated Interferon?

GlossaryPegylated Interferon

modified interferon with polyethylene glycol for prolonged therapeutic effect

Pegylated Interferon, often abbreviated as PEG-IFN, is a modified form of interferon used to treat certain viral infections and cancers. The "pegylation" process involves attaching polyethylene glycol (PEG) molecules to the interferon, which helps to prolong its presence in the bloodstream, reduce the frequency of dosing, and minimize side effects. This modification enhances the therapeutic efficacy and patient compliance compared to standard interferon treatments.

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Exacerbation of Alopecia Areata During Pegylated Interferon Alpha-2b and Ribavirin Therapy, Possibly Due to the Collapse of Hair Follicle Immune Privilege

research Exacerbation of alopecia areata during pegylated interferon alpha-2b and ribavirin therapy, possibly due to the collapse of hair follicle immune privilege

10 citations , September 2014 in “European Journal of Dermatology”

A woman's hair loss worsened after starting hepatitis C treatment due to immune changes in her hair follicles.

Dystrophic Anagen Effluvium Occurring During Pegylated Interferon-α-2a/Ribavirin Therapy

research Dystrophic-Anagen Effluvium Occurring During Pegylated Interferon-α-2a/Ribavirin Therapy

2 citations , March 2015 in “Hepatitis Monthly”

A woman's hair loss during Hepatitis C treatment with PEG-INF-a-2a and Ribavirin was reversible after stopping the medication.

Alopecia Universalis as a Side Effect of Pegylated Interferon α-Ribavirin Combination Therapy for Hepatitis C: A Rare Case Report

research Alopecia universalis as a side effect of pegylated interferon α-ribavirin combination therapy for hepatitis C: a rare case report

6 citations , October 2016 in “Journal of Chemotherapy”

A man lost all his hair as a rare side effect after hepatitis C treatment.

Alopecia Universalis Following Interferon Alfa-2b and Ribavirin Treatment for Hepatitis C

research Alopecia universalis following interferon alfa-2b and ribavirin treatment for hepatitis C.

4 citations , August 2007 in “PubMed”

A woman lost all her body hair after hepatitis C treatment, but it started to grow back a year after stopping the treatment.

Cutaneous Necrosis After Injection of Polyethylene Glycol–Modified Interferon Alfa

research Cutaneous necrosis after injection of polyethylene glycol–modified interferon alfa

26 citations , June 2005 in “Journal of The American Academy of Dermatology”

Some patients receiving pegylated interferon alfa injections developed skin necrosis, requiring treatment adjustments or discontinuation.

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