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GlossaryInterferons

Interferons are a group of signaling proteins produced by the immune system in response to viral infections and other stimuli. They play a crucial role in regulating immune responses and have been studied for their potential effects on hair biology, particularly in conditions like alopecia areata, where they may help modulate inflammation and promote hair regrowth. Key distinguishing characteristics of interferons include their ability to enhance the activity of immune cells and their role in inhibiting viral replication, which can indirectly influence hair follicle health and cycling.

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Research

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Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment

research Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

278 citations , March 2013 in “Gut”

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

research Interferon alfa-2a in the treatment of cutaneous T cell lymphoma

209 citations , March 1989 in “Journal of The American Academy of Dermatology”

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

research Interferon in the treatment of cutaneous T-cell lymphoma

107 citations , December 2003 in “Dermatologic Therapy”

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

research Reversible Alopecia Universalis During Treatment with PEG-Interferon and Ribavirin for Chronic Hepatitis C

27 citations , April 2005 in “Journal of Chemotherapy”

Some patients may experience temporary total hair loss from hepatitis C treatment with PEG-interferon and ribavirin.

research INTERFERONS IN DERMATOLOGY

22 citations , April 1998 in “Dermatologic Clinics”

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

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community Combining topicals together or use them separately

in Chat 4 upvotes 11 months ago

Combining Minoxidil with Finasteride or RU58841 may cause interference, irritation, or reduced absorption. It might be better to apply one topical at a time and wait an hour before applying another.

community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 44 upvotes 3 years ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community 31M, Using Minoxidil for 5 Months, Considering Finasteride – How to Assess Responsiveness?

in General 201 upvotes 9 months ago

A 27-year-old male has been using minoxidil for five months with no improvement and is considering adding finasteride to address potential DHT interference. He is seeking advice on whether finasteride might enhance minoxidil's effectiveness or if he should consider other options like a hair transplant.

community Progress update: 4 months 10days of using topical minoxidil.

in Is this regrowth? 43 upvotes 1 year ago

The user experienced hair regrowth after using 5% topical minoxidil for over four months, despite initial shedding. They apply it once daily but occasionally skip days due to concerns about collagen production interference.

community Shoutout to Zinc pyrithione and Piroctone olamine

in Product 3 upvotes 1 year ago

Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

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