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GlossaryPermanent Chemotherapy-Induced Alopecia

long-term hair loss caused by chemotherapy treatment

Permanent Chemotherapy-Induced Alopecia (PCIA) refers to the long-term or irreversible loss of hair as a result of chemotherapy treatment. Unlike temporary hair loss, which is common during chemotherapy and usually resolves within months after treatment ends, PCIA means that the hair does not regrow, or regrows very sparsely, even after the completion of chemotherapy. This condition can significantly impact a patient's quality of life and self-esteem.

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Research

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research Permanent chemotherapy-induced alopecia: Case report and review of the literature

67 citations , May 2010 in “Journal of The American Academy of Dermatology”

Some chemotherapy can cause permanent hair loss.

research Permanent Chemotherapy-Induced Alopecia in Patients with Breast Cancer: A 3-Year Prospective Cohort Study

59 citations , August 2018 in “The oncologist”

Some breast cancer patients still experience hair loss three years after chemotherapy, especially with taxane-based treatments.

research Treatment of permanent chemotherapy-induced alopecia with low dose oral minoxidil

36 citations , May 2015 in “Australasian Journal of Dermatology”

Low dose oral minoxidil helps regrow hair in permanent chemotherapy-induced alopecia.

research Permanent chemotherapy-induced nonscarring alopecia and premature ovarian failure

5 citations , March 2015 in “Clinical and Experimental Dermatology”

Chemotherapy caused a woman's permanent hair loss and early menopause.

research Permanent chemotherapy-induced alopecia after hematopoietic stem cell transplantation treated with low-dose oral minoxidil

4 citations , February 2022 in “JAAD case reports”

The document concludes that low-dose oral minoxidil successfully regrew hair in a patient with permanent hair loss after chemotherapy and stem cell transplant.

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 67 upvotes 10 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 208 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 114 upvotes 1 year ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community It's always the Mice that gets to grow back hair.

in Research/Science 431 upvotes 9 months ago

Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

community The case of a 78 year old man who accidentally regrew his hair (published in the British Medical Journal)

in Chat 213 upvotes 9 months ago

A 78-year-old man regrew hair after suffering burns, suggesting that injury-induced healing processes might trigger hair growth. Microneedling and other treatments like minoxidil and finasteride are discussed as potential methods to stimulate similar regrowth.

View more "permanent chemotherapy-induced alopecia" in community →