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research Coconut oil works as a gonadal feedback testosterone booster and increases pituitary aromatase (cyp19a1b) expression levels in fugu (Takifugu rubripes)

October 2025 in “Aquaculture”

Coconut oil boosts testosterone but doesn't fully trigger reproductive maturity in pufferfish.

research Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones

197 citations , January 2019 in “Neuropsychopharmacology”

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms

research Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms

18 citations , June 2009 in “Journal of Molecular Endocrinology”

Finasteride exposure harms tadpole reproduction and hormone balance.

research Fertility and sexual life of men after their forties and in older age.

26 citations , March 2001 in “PubMed”

Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.

research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male

70 citations , March 2016 in “Urologic Clinics of North America”

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

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community Methods Of Staying Safe On Ru58841 - My 2 Cents

in Research/Science 21 upvotes 1 year ago

RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

community Pyrilutamide: Increased libido. Anyone else experienced something similar with either RU or Pyri?

in Product 18 upvotes 3 years ago

An increase in libido associated with the use of Pyri, and a discussion about how it may be working comparably to other hair loss treatments such as RU58841, Finasteride and Minoxidil.

community This could be it!!! New treatment increase hair 500%

in Research/Science 343 upvotes 8 months ago

Clascoterone (Breezula) shows a potential 500% increase in hair growth, possibly outperforming minoxidil and finasteride. It is in advanced trials, with hopes for FDA approval, but cost and side effects are concerns.

community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 117 upvotes 3 years ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

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