Fertility and Sexual Life of Men After Their Forties and in Older Age

March 2001 in “ PubMed ”

Wolf‐Bernhard Schill

spermatogenesis Leydig cells sex hormone pituitary-gonadal feedback LH FSH testosterone androgen supplementation partial androgen deficiency in aging males luteinizing hormone follicle-stimulating hormone testosterone therapy PADAM

TLDR Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.

The document reviewed the effects of aging on male fertility and sexual health, noting that while spermatogenesis can continue into old age, about 50% of men in their eighties experienced complete loss of fertility. Aging in men was characterized by a decline in Leydig cells, leading to altered sex hormone levels and impaired pituitary-gonadal feedback, with increased LH and FSH levels and reduced testosterone bioavailability. Men over 60 showed signs of reduced virility, such as decreased muscle mass, strength, and libido. The study suggested androgen supplementation could be beneficial, but highlighted the need for more research and long-term risk-benefit studies, particularly concerning partial androgen deficiency in aging males (PADAM).

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research Fertility and Sexual Life of Men After Their Forties and in Older Age

26 citations , March 2001 in “PubMed”

Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.

research Fertility and Sexual Life of Men After Their Forties and in Older Age

January 2001 in “亚洲男性学杂志：英文版”

Men's fertility and sexual health decline with age, but some remain fertile into their eighties.