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GlossaryPolydispersity Index

measure of molecular size distribution in a polymer sample

The Polydispersity Index (PDI) is a measure of the distribution of molecular mass in a given polymer sample. It indicates how uniform or varied the sizes of the molecules are within the sample. A PDI value close to 1 suggests a uniform molecular size, while higher values indicate a broader range of molecular sizes. This term is particularly important in fields like materials science and biochemistry, where the consistency of molecular size can impact the properties and behavior of materials or biological molecules.

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research Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases

26 citations , July 2023 in “International Journal of Nanomedicine”

The microneedle system shows promise for non-invasive brain drug delivery.

Self-Assembled Chitosan Nanoparticles for Percutaneous Delivery of Caffeine: Preparation, Characterization, and In Vitro Release Studies

research Self-Assembled Chitosan Nanoparticles for Percutaneous Delivery of Caffeine: Preparation, Characterization, and In Vitro Release Studies

7 citations , July 2018 in “International Journal of Applied Pharmaceutics”

Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.

Improvement in Physicochemical Parameters of DPPC Liposomes and Increase in Skin Permeation of Aciclovir and Minoxidil by the Addition of Cationic Polymers

research Improvement in Physicochemical Parameters of DPPC Liposomes and Increase in Skin Permeation of Aciclovir and Minoxidil by the Addition of Cationic Polymers

61 citations , June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics”

Cationic polymers improved liposome stability and increased skin absorption of aciclovir and minoxidil.

research Optimization, Characterization, and Follicular Targeting Assessment of Tretinoin and Bicalutamide Loaded Niosomes

16 citations , November 2023 in “Scientific Reports”

The niosomes effectively target hair follicles for acne treatment.

research Traditional Knowledge Digital Library: The Challenges Ahead

1 citations , January 2017 in “Social Science Research Network”

The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.

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community Does anyone know the chemical formula for pelage pp405?

in Research/Science 14 upvotes 10 months ago

The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 46 upvotes 2 years ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community Topical Finasteride that doesn’t go systematic is the cure

in Treatment 3 upvotes 10 months ago

Topical finasteride that doesn't penetrate the skin could potentially treat hair loss without side effects. Current challenges include finding a formulation that remains on the scalp without increasing blood levels.