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GlossaryPOU domain

specific protein region that binds DNA to regulate genes

The POU domain is a specific region found in certain proteins that bind to DNA and regulate gene expression. Named after three transcription factors (Pit-1, Oct-1/2, and Unc-86), this domain is crucial for the development and function of various tissues, including the nervous system and the immune system.

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research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes

74 citations , October 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

research Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain during Epidermal Differentiation

25 citations , October 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.

research The History of Hair Transplantation

15 citations , March 2000 in “Dermatologic Surgery”

Hair transplantation has evolved since 1822, with significant advancements by key figures and widespread international growth.

research The epidermis: rising to the surface

238 citations , October 1994 in “Current opinion in genetics & development”

The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.

research Hox genes in development and beyond

83 citations , January 2023 in “Development”

Hox genes are crucial for development and tissue maintenance, affecting structures and functions throughout life.

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