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    GlossaryPregnenolone

    steroid hormone precursor to progesterone, estrogen, testosterone, and cortisol

    Pregnenolone is a steroid hormone that serves as a precursor to various other hormones, including progesterone, estrogen, testosterone, and cortisol. It is synthesized from cholesterol in the adrenal glands, liver, and brain, playing a crucial role in the body's hormonal balance and overall health.

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      community Crazy question about sex sides

      in General  50 upvotes 11 months ago
      The conversation discusses using hormones like pregnenolone and tongkat ali to counteract sexual side effects from hair loss medications such as finasteride, dutasteride, ketoconazole, and minoxidil. The user stopped the other medications but continues using minoxidil while seeking advice on maintaining libido.

      community No longer have drive in the gym

      in Chat  8 upvotes 2 weeks ago
      The user lost gym motivation after taking finasteride for four months, possibly due to its effect on DHT levels. Suggestions include adjusting dosage, trying topical treatments, using caffeine, checking testosterone levels, and considering supplements like SSRIs or pregnenolone.

      community My Estradiol Level on Finasteride

      in Research/Science  17 upvotes 11 months ago
      Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

      community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

      in Treatment  49 upvotes 5 years ago
      A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.