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      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

    Research

    5 / 1000+ results
      The Pathogenesis of Primary Cicatricial Alopecias

      research The Pathogenesis of Primary Cicatricial Alopecias

      150 citations , October 2010 in “The American Journal of Pathology”
      The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
      Primary Cicatricial Alopecia: Treatment Approaches and Classification

      research Primary cicatricial alopecia

      95 citations , November 2016 in “Journal of The American Academy of Dermatology”
      Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.
      Primary Cicatricial Alopecia

      research Primary cicatricial alopecia

      65 citations , November 2016 in “Journal of The American Academy of Dermatology”
      The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

    Community Join

    5 / 484 results

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  97 upvotes 1 year ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  55 upvotes 1 year ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Can we get a reality check on PP405?

      in Research/Science  80 upvotes 5 months ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.