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GlossaryProstaglandin D2 Receptor

protein on cell surfaces that binds prostaglandin D2, affecting hair growth

The Prostaglandin D2 Receptor (often abbreviated as PTGDR or PTGDR2) is a protein found on the surface of certain cells that binds to prostaglandin D2, a type of lipid compound involved in various physiological processes. This receptor plays a significant role in inflammatory responses and has been linked to conditions like asthma and hair loss, particularly androgenetic alopecia, where its activation can inhibit hair growth.

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Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (Capra hircus) Skin During Hair Follicle Development

research Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development

2 citations , February 2014 in “Animal Biotechnology”

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

research Expression Level of Prostaglandin D2 Receptor 2 Regulates Hair Regression

2 citations , February 2019 in “Journal of Investigative Dermatology”

Higher levels of the DP2 receptor may lead to hair loss.

research Prostaglandin E ₂ Receptor 2 Modulates Macrophage Activity for Cardiac Repair

29 citations , September 2018 in “Journal of the American Heart Association”

EP 2 receptor is essential for heart repair by helping macrophages work properly.

research Recent Progress in Prostaglandin F 2a Ethanolamide (Prostamide F2a) Research and Therapeutics

1 citations , January 2013

Bimatoprost treats glaucoma and promotes hair growth, with potential for more medical uses.

research 850 After skin wounding, noncoding dsRNA coordinates prostaglandins and WNT7b to promote regeneration

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Double stranded RNA helps skin wounds heal by coordinating specific proteins and signaling pathways.

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community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

in Research/Science 3 upvotes 1 year ago

DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

community Chromosome 20’s balding effects and why fin likely isn’t working for some.

in Treatment 96 upvotes 10 months ago

Finasteride is effective for DHT/AR-driven hair loss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hair loss to tailor treatment effectively.

community You will lose hair if your prostaglandins aren't in balance

in Research/Science 56 upvotes 1 year ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 94 upvotes 6 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Doubts about castor oil

4 upvotes 7 years ago

Castor oil's effectiveness for hair growth is debated, with concerns about its impact on skin health and prostaglandin levels. Some users suggest combining it with coconut oil and using it alongside finasteride for better results, while others recommend sticking to proven synthetic treatments.

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