Search
for

    Did you mean Prostaglandin D2 Synthase?
    GlossaryProstaglandin D2 Synthase

    enzyme converting prostaglandin H2 to prostaglandin D2, linked to hair loss

    Prostaglandin D2 Synthase (PTGDS) is an enzyme that converts prostaglandin H2 into prostaglandin D2 (PGD2), a lipid compound involved in various physiological processes, including inflammation and allergic responses. In the context of hair biology, elevated levels of PGD2 have been linked to hair loss, particularly in conditions like androgenetic alopecia.

    Related Terms

    Learn

    5 / 801 results

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Cetirizine

      popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

      learn Latanoprost

      glaucoma medication with hair follicle stimulant effects

    Research

    5 / 1000+ results

    Community Join

    5 / 107 results

      community Castor Oil - Yay or Nay?

      in Product  8 upvotes 5 years ago
      The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.

      community Doubts about castor oil

       4 upvotes 7 years ago
      Castor oil's effectiveness for hair growth is debated, with concerns about its impact on skin health and prostaglandin levels. Some users suggest combining it with coconut oil and using it alongside finasteride for better results, while others recommend sticking to proven synthetic treatments.

      community Painkillers May Block Minoxidil

      in Research/Science  16 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community Setipiprant/PGE2 feedbacks?

      in Question  4 upvotes 8 years ago
      The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.