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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 1000+ resultsresearch Analysis of Hairless Corepressor Mutants to Characterize Molecular Cooperation with the Vitamin D Receptor in Promoting the Mammalian Hair Cycle
Certain mutations in the hairless protein disrupt its ability to regulate the hair cycle.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Candidate Genes of SARS-CoV-2 Gender Susceptibility
The study investigated gender susceptibility to SARS-CoV-2 by analyzing molecular variations in proteins expressed in gonadal tissues, finding that men were more affected by COVID-19 due to differences in immune responses and protein expression like ACE2 and TMPRSS2. It identified specific genes in testicular and ovarian networks, such as TMPRSS2, ADAM10, SERPING1, and CCR5 in testis, and BST2, GATA1, ENPEP, TLR4, TLR7, IRF1, and IRF2 in ovaries, which may contribute to variable susceptibility and severity. The study suggested that male sex hormones could facilitate viral entry, while estrogen might offer protection. It also highlighted the role of the complement system in COVID-19 pathogenesis and the complex interplay of genetic factors influencing disease severity and outcomes, emphasizing the need for further research to develop diagnostic and therapeutic strategies.
research LncRNA MTC Enhances the Proliferation of Liaoning Cashmere Goat Skin Fibroblasts by Modulating GSTM1-ASK1 Interaction
LncRNA MTC boosts growth of goat skin cells, improving cashmere quality.
research Virtual Screening of MAP-Tau Protein Inhibitors from Semecarpus Anacardium Linn. Leaf Extract for Cancer Prevention
Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.
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5 / 752 resultscommunity Topical fin and min and swallowing semen
A user asked if it's safe to swallow semen from a partner using topical finasteride and minoxidil. Responses varied, but most suggested it's likely safe, with minimal risk from small amounts of finasteride in semen.
community 2020-2025, progress slowed down and now it’s plateaued
The user has been using finasteride and topical minoxidil since 2020 with good initial results, but progress has stalled since 2024. They are considering switching to dutasteride and oral minoxidil for better results.
community Better Than Minoxidil? Topical Sodium Valproate
Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.
community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.
Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.
community Creatine is the opposite of minoxidil !
Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.