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GlossaryPsoriasis Area and Severity Index

tool measuring psoriasis severity and affected body area

The Psoriasis Area and Severity Index (PASI) is a tool used by healthcare professionals to measure the severity and extent of psoriasis, a chronic skin condition. It combines the assessment of the redness, thickness, and scaling of the skin lesions with the percentage of body surface area affected, providing a score that helps guide treatment decisions and monitor disease progression.

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Facial Psoriasis Log-Based Area and Severity Index: A Valid and Reliable Severity Measurement Method Detecting Improvement of Facial Psoriasis in Clinical Practice Settings

research Facial Psoriasis Log-based Area and Severity Index: A valid and reliable severity measurement method detecting improvement of facial psoriasis in clinical practice settings

2 citations , March 2016 in “The Journal of Dermatology”

The Facial Psoriasis Log-based Area and Severity Index is a more effective way to measure improvements in facial psoriasis than the traditional method.

research Real-world single-center experience with 10 cases of generalized pustular psoriasis successfully treated with ixekizumab

21 citations , September 2019 in “Journal of the American Academy of Dermatology”

Ixekizumab effectively treats generalized pustular psoriasis.

research Dovobet ointment under occlusion overnight for troublesome scalp psoriasis

8 citations , April 2006 in “Acta dermato-venereologica”

Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.

research Narrowband UVB treatment induces expression of WNT7B, WNT10B and TCF7L2 in psoriasis skin

5 citations , May 2019 in “Archives of Dermatological Research”

Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.

Efficacy and Safety of Topical Rosuvastatin and Melatonin vs. Placebo in Patients with Mild to Moderate Plaque Psoriasis: A Preliminary Randomized Double-Blinded Clinical Trial

research Efficacy and safety of topical rosuvastatin & melatonin vs. placebo in patients with mild to moderate plaque psoriasis: A preliminary randomized double‐blinded clinical trial

1 citations , April 2024 in “Skin research and technology”

Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 416 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 94 upvotes 6 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community What's "wrong" with oral minoxidil, exactly?

in Minoxidil 173 upvotes 1 year ago

Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 41 upvotes 1 year ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

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