research Selective non-steroidal inhibitors of 5α-reductase type 1
Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
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research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Androgens and alopecia
Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
research Analysis of metabolic characteristics of epristeride in zebrafish based on LC-Q-TOF MS and its potential applications in doping control
Epristeride's metabolism in zebrafish helps improve doping detection methods.
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2 / 1000+ resultscommunity This is what Six years of DUT looks like
User had success with dutasteride for hair loss after finasteride didn't work. Some experienced increased cholesterol and debated its relation to DHT.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
Clinics
5 / 5 results- 15TrichologyRA Skin and Hair ClinicLal Bahadur Nagar, Telangana · IN
- 27Hair Loss TreatmentsDermatologyRa'Derm ClinicBhiwandi, Maharashtra · IN
- 23Hair SystemsRA PROTÉSIS CAPILARES COSTA RICASan Vicente · CR
- 47
Hair TransplantDermatologyInstituto RA – Dermatologia & EspecialidadesPalmas, TO · BR - 33
Hair SystemsR & A Fuller HairworldLeeds · GB
Experts
6 / 20 results- 76
DermatologistDr. Rhea Shetty, MBBS
Mumbai, Maharashtra, India
- 61Hair Transplant Surgeon
Dr. Raya Brodskiy, MD
Virginia Beach, VA, United States
- 79
SMP SpecialistRay Diaz
Charlotte, NC, United States
- 89
Hair Transplant SurgeonDr. Roy B. Stoller, MD
New York, NY, United States
- 87
Hair Transplant SurgeonDr. Rae Lynne Kinler, MD
Greenwich, CT, United States
- 64
DermatologistRia Rai Pandey, MD
Varanasi, Uttar Pradesh, India