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Tofacitinib was effective for severe, treatment-resistant hair loss without side effects.

Liquid nitrogen cryotherapy worked well for many patients with stubborn alopecia areata.

Topical metformin may improve hair regrowth in CCCA when added to standard treatments.

Combination therapy, including JAK inhibitors, effectively regrows hair and reduces severity in Black children with stubborn Alopecia Areata.

Two patients with stubborn hair loss grew hair after PDRN injections.