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cellular communication process involving protein receptors that regulate growth

Receptor Tyrosine Kinase (RTK) Signaling is a cellular communication process where specific proteins on the cell surface, known as receptor tyrosine kinases, bind to signaling molecules like growth factors. This binding activates the receptors, causing them to add phosphate groups to certain tyrosines on themselves and other proteins, which then triggers a cascade of intracellular events that regulate cell growth, division, and survival. This pathway is crucial in many biological processes and is often implicated in diseases such as cancer when dysregulated.

Related Terms

• Tyrosine Kinase
• T cell receptor signaling
• KIT Proto-Oncogene Receptor Tyrosine Kinase
• ERK Pathway
• Extracellular Signal-Regulated Kinase
• Transforming Growth Factor Beta Receptor 1
• Tropomyosin receptor kinase A
• Signaling Pathways