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GlossaryReconstructed Human Epidermis

laboratory-grown model of human skin for research and testing

Reconstructed Human Epidermis (RHE) is a laboratory-grown model of human skin created from cultured human skin cells. It mimics the structure and function of the outermost layer of the skin, making it a valuable tool for testing cosmetics, pharmaceuticals, and studying skin biology without the need for animal testing.

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Research

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Expression of Type 1 5α-Reductase and Metabolism of Testosterone in Reconstructed Human Epidermis: A New Model for Screening Skin-Targeted Androgen Modulators

research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators

3 citations , December 2000 in “International Journal of Cosmetic Science”

The study created a new method to test drugs that affect hormone processing in skin.

Study of the Impact of SKPs' Secreted Factors and a Botanical Extract Derived from Jasmine on Keratinocyte Growth and Reconstructed Human Epidermis Thickness

research 692 Study of the impact of SKPs’ secreted factors and of a botanical extract derived from jasmine on keratinocytes growth and reconstructed human epidermis thickness

April 2016 in “Journal of Investigative Dermatology”

Jasmine extract helps skin cell growth and makes artificial skin thicker, especially when used with skin-derived precursors.

research Epidermis reconstructed from the outer root sheath of human hair follicle. Effect of retinoic acid

18 citations , June 1993 in “Archives of Dermatological Research”

Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.

research 890 Development of pigmented reconstructed human epidermis model containing human melanoblasts from keratinocyte culture

April 2019 in “Journal of Investigative Dermatology”

The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.

research Epidermis reconstructed from the outer root sheath of human hair follicle on de-epidermized dermis. Effect of retinoic acid

August 1993 in “Journal of Dermatological Science”

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Community Join

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community Hair and normal skin created from human pluripotent stem cells for the first time

in Update 86 upvotes 6 years ago

Human pluripotent stem cells have been used to create hair and skin, potentially offering a new solution for baldness. A user also mentioned starting finasteride but experiencing unexpected hair thinning.

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Learn

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learn Epidermal Growth Factor

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12
SMP
Maison EpidermisOrléans · FR

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