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GlossaryRegeneration

biological process of replacing or restoring lost tissues

Regeneration refers to the biological process by which organisms replace or restore lost or damaged tissues, organs, or cells. In the context of hair, it involves the renewal of hair follicles and the growth of new hair strands, often influenced by factors like genetics, hormones, and overall health.

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Research

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research Comparative Transcriptome Analysis of the Regenerating Zebrafish Telencephalon Unravels a Resource With Key Pathways During Two Early Stages and Activation of Wnt/β-Catenin Signaling at the Early Wound Healing Stage

33 citations , October 2020 in “Frontiers in Cell and Developmental Biology”

Wnt/β-catenin signaling is crucial for early zebrafish brain regeneration.

research Integral characterization of normal and alopecic hair at different degeneration stages by in-situ visible and chemical imaging

13 citations , March 2020 in “Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy”

Alopecic hair has more irregular structures and chemical changes than normal hair, reducing its strength.

K15 And Id3 Expression In Intact And Regenerating Adult Vibrissae Rodent Hair Follicles

research K15 & Id3 expression in intact and regenerating adult vibrissae rodent hair follicles

January 2009

K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.

research Resting no more: re‐defining telogen, the maintenance stage of the hair growth cycle

120 citations , November 2014 in “Biological Reviews”

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

research Reflectance spectroscopy for noninvasive evaluation of hair follicle stage

1 citations , November 2014 in “Journal of Biomedical Optics”

Reflectance spectroscopy can noninvasively track hair growth stages by measuring skin reflectance and melanin changes.

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Community Join

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community Has anyone here actually undergone experimental (grey market) hair cell therapy/follicle cloning?

in Technology 6 upvotes 4 months ago

Hair cell therapy and follicle cloning are still in experimental stages, with treatments like hair multiplication and regenerative hair therapy being marketed but not yet proven to create unlimited new follicles. There is skepticism about the effectiveness and legitimacy of these treatments, with some considering them scams.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

in Research/Science 30 upvotes 4 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026 28th march

in Research/Science 29 upvotes 4 months ago

Pelage Pharmaceuticals' PP405 aims to treat hair loss by reactivating dormant hair follicle stem cells, showing promising results in early trials. The company plans to present their findings at the American Academy of Dermatology Annual Meeting in 2026.

community Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026

in Research/Science 126 upvotes 4 months ago

PP405 shows promise in regenerating hair by activating dormant follicles. Other treatments like VDPHL01 and Breezula are also advancing, providing new hope for hair loss solutions.

community Verteporfin update - donor hair regeneration human trial

in Research/Science 23 upvotes 3 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Rapamycin

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Thymosin Beta 4

learn Epidermal Growth Factor

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Clinics

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Experts

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