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GlossaryEpithelial Regeneration

process of skin and organ lining cells repairing themselves

Epithelial regeneration refers to the process by which the epithelial cells, which form the outer layer of the skin and line various organs and structures in the body, repair and renew themselves after injury or damage. This process is crucial for maintaining the integrity and function of tissues, as it involves the proliferation and differentiation of stem cells to replace lost or damaged cells.

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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Research

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research Plasticity of Epithelial Stem Cells in Tissue Regeneration

479 citations , June 2014 in “Science”

Epithelial stem cells can adapt and help in tissue repair and regeneration.

research Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish

92 citations , March 2016 in “Developmental Cell”

Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.

research Immune-Epithelial Cross Talk in Regeneration and Repair

52 citations , January 2023 in “Annual Review of Immunology”

Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.

research In Vitro Skin Models to Study Epithelial Regeneration from the Hair Follicle

19 citations , March 2017 in “PLoS ONE”

PSU are better than THF at regenerating skin layers in lab models.

research Scaffolds for Epithelial and Hair Follicle Regeneration

1 citations , January 2019 in “Elsevier eBooks”

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

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Community Join

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community Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling

in Research/Science 22 upvotes 3 months ago

Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.

community Researchers working on ways to regenerate lost hair from stem cells identified a recipe for normal hair regeneration in the lab. “A method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future.”

in Research/Science 260 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.

community Got my Oleic fatty acid they used in Korean study. Fuck you mice!

in Research/Science 241 upvotes 3 weeks ago

Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.

community Microneedling and aloe vera to recruit stem cells.

in Chat 11 upvotes 2 years ago

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 105 upvotes 3 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

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