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research Cell death as an architect of adult skin stem cell niches

April 2024 in “Cell death and differentiation”

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

research Profiling the Response of Human Hair Follicles to Ultraviolet Radiation

53 citations , January 2009 in “Journal of Investigative Dermatology”

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

research Complications and Difficult Cases: A Case Report of Central Area Necrosis Following a Hair Transplant Procedure

March 2014 in “Hair transplant forum international”

A man experienced skin death after a hair transplant, likely due to poor blood supply related to his smoking habit.

research Cell death by cornification

375 citations , June 2013 in “Biochimica et biophysica acta. Molecular cell research”

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

research N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting

76 citations , June 2015 in “Journal of biomedical science”

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

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community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 11 months ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community Minoxidil is NOT an Anti-androgen. No.

in Research/Science 43 upvotes 8 months ago

Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.

community The meds work: my dad at 23 yo vs me at 35 yo

in Finasteride/Dutasteride 1790 upvotes 1 year ago

Finasteride and oral minoxidil effectively maintain a youthful appearance and full head of hair, despite genetic predispositions to balding. The discussion also considers the impact of DHT blockers on masculinity and aging, with lifestyle choices like sunscreen use and a vegetarian diet mentioned.

community When you're balding is it an absolute traumatic period of your life or do some people not care as much?

in Chat 89 upvotes 2 years ago

Balding can be traumatic for many, affecting self-esteem and social interactions, while others accept it more easily. Treatments mentioned include finasteride, minoxidil, and RU58841.

community C’est terrible - at my wits end

in Female 450 upvotes 2 years ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

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