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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

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      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  170 upvotes 1 month ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  19 upvotes 1 month ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community Why doesn't phase 3 of PP405 start straight away?

      in Chat  14 upvotes 3 weeks ago
      Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.