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The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Excess maternal androgens can cause heart problems in offspring.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Curcumin shows promise in reducing pain and inflammation, but more research is needed.

5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.

Hepatitis B virus alters steroid hormones in male mice, reducing dihydrotestosterone to inhibit viral replication.

Hair analysis can help diagnose adrenal disorders non-invasively.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.