May 2026 in “Frontiers in Pharmacology” The study investigates the effects of Dendrobium officinale polysaccharide (DOP) on hair regrowth in androgenetic alopecia (AGA) mice. Results indicate that DOP improves hair regrowth in a dose-dependent manner, with the high-dose group showing significant improvements in hair coverage, follicle density, dermal thickness, hair bulb diameter, and anagen phase proportion. The treatment was linked to decreased SRD5A1 expression, increased CYP19A1 expression, reduced local dihydrotestosterone and testosterone levels, and elevated p-ESR1 and KRT28/KRT71 expression. These changes suggest that DOP influences local steroid metabolism, ESR1 activation, and keratin-related follicular responses, enhancing follicular morphology and cycling. The findings propose a framework for further exploration of DOP in treating AGA.
July 2025 in “Scientific Reports” RG and RJ gels speed up burn wound healing better than other treatments.
158 citations
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June 2014 in “Journal of Lipid Research” Lysophospholipids can act as anti-inflammatory agents through specific receptors, but more research is needed.
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February 1975 in “Journal of Steroid Biochemistry” 31 citations
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January 1998 in “Endocrine journal” Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
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December 2020 in “Endocrine-related Cancer” The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.
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April 2004 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New progesterone-based compounds can block male hormones.
May 2022 in “Reactions Weekly” 
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July 2021 in “Drug Testing and Analysis” 5α-reductase inhibitors can interfere with doping tests by masking banned substances.
April 2024 in “The Journal of urology/The journal of urology” 5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.
November 2024 in “Journal of Investigative Dermatology” Polygenic Score can help predict severe psoriasis and psoriatic arthritis.
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March 2003 in “Steroids” PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
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June 2024 in “International Journal of Drug Delivery Technology” Advanced delivery systems can make dithranol more effective and less irritating for treating psoriasis.
March 2017 in “Zenodo (CERN European Organization for Nuclear Research)” L. plantarum MTCC 1325 may help improve memory and cognitive functions in Alzheimer's.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
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January 2014 in “Journal of Controlled Release” This method is effective for needle-free HIV-1 vaccination by activating immune responses in the skin.
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July 2009 in “Experimental and clinical endocrinology & diabetes” Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
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January 2014 The F9 formulation of Finasteride tablets, using Eudragit, successfully controlled drug release.
403 citations
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November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
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January 1989 in “The Prostate/The prostate” Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.
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May 2023 in “Cancer Nanotechnology” The new drug delivery system effectively targets lung cancer cells.
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October 2021 in “Journal of Nanobiotechnology” HPDAlR nanoparticles greatly improve skin wound healing without toxicity.
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May 2020 in “Molecules” A new, efficient method was developed to synthesize a specific compound and its derivatives.
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September 2024 in “Journal of Microbiology and Biotechnology” Human placenta extract reduces inflammation and symptoms in atopic dermatitis.
May 2026 in “Reactions Weekly” April 2026 in “Reactions Weekly” December 2024 in “Reactions Weekly” November 2014 in “Reactions Weekly” July 2014 in “Reactions Weekly”