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A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

A new method creates unique chemical structures that could improve drug discovery.

The protein AtRXR3 limits root hair growth in Arabidopsis, affecting phosphorus uptake.

The study identified a key protein involved in producing underarm odor and found ways to inhibit it.

Local positive feedback helps shape root hair cells by stabilizing growth sites.

Researchers made two new compounds that could be used for medicine.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

OR2AT4 helps reduce aging and cell damage in human skin cells.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Reduced Stx17 expression may contribute to Alopecia Areata.

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.

A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.

Robertsonian translocation can cause recurrent miscarriages.

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.

A gene network led by RSL4 is crucial for early root hair growth in response to cold in Arabidopsis thaliana.

HB24 helps convert IBA to IAA, promoting root hair growth.

Changing Allopregnanolone levels in newborns affects adult behavior and anxiety.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Krox20 (Egr2) is important for the function of epithelial stem cells.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

The B2 genes are crucial for hair growth in rats.