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Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

A new compound effectively inhibits human 5α-reductase 1.

A new, efficient method was developed to synthesize a specific compound and its derivatives.

The new compounds may be more effective and cheaper than current treatments for conditions like baldness.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Scientists made two new chemicals that might help treat diseases caused by male hormones.

Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

A new method to make Finasteride is more cost-effective and yields 16%.

3α‐OH‐DHP is essential for reducing nerve activity related to blood pressure control during pregnancy.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

DPCP may be safe for treating alopecia during pregnancy, but more research is needed.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

New progesterone-based compounds can block male hormones.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

CB-03-04 shows promise as a treatment for prostate issues due to its strong anti-androgen effects.

Diane is effective for treating acne, seborrhoea, androgenic alopecia, and mild hirsutism in women.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

A new method was developed to make finasteride for treating hair loss.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.