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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

5-alpha reductase inhibitors don't increase breast cancer or benign breast disorder risk in women.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.

A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

17β-Estradiol slows wound healing in male mice through estrogen receptor-α.

5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.

Estradiol stops hair growth in mice, but an antagonist can reverse this effect.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

17β-estradiol can reduce inflammation in the skin.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

Hair loss can be treated with common methods like minoxidil and finasteride, but new potential treatments include growth factors, cytokines, and platelet-rich plasma injections.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.

People with lower levels of free testosterone tend to have worse COVID-19 outcomes.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.