50 citations
,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
46 citations
,
August 2006 in “PubMed” A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.
42 citations
,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
37 citations
,
January 1980 in “PubMed” Hair lotions with 17 alpha-estradiol can reduce hair loss but won't regrow new hair.
32 citations
,
December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” 17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.
26 citations
,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
25 citations
,
September 2015 in “Clinical Endocrinology” Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.
18 citations
,
August 2008 in “Journal of Investigative Dermatology” 17-β estradiol and prednisolone may speed up hair regrowth after chemotherapy.
10 citations
,
November 2019 in “Neuroendocrinology” Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.
10 citations
,
March 1973 in “Journal of Investigative Dermatology”
10 citations
,
August 2018 in “Dermatologic Surgery” Laser treatment improves hair density and increases growth factors in androgenetic alopecia.
9 citations
,
April 2016 in “Clinical Endocrinology” Scalp hair 17-OHP and androstenedione levels can help monitor treatment in CAH patients.
7 citations
,
October 2019 in “Case reports in endocrinology” A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.
6 citations
,
January 1984 in “PubMed” Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.
5 citations
,
July 2021 in “Endocrinology, diabetes & metabolism” Glioblastoma cells can make androgens, which might help the tumor grow.
1 citations
,
August 2015 in “PubMed” A woman with non-classic CAH had unusual heavy periods and high hormone levels, improved with treatment.
August 2025 in “American Journal of Case Reports” Accurate diagnosis and early specialist referral are crucial for managing 46,XY Disorders of Sex Development.
TrichoSol™ effectively stabilizes various hair treatment ingredients for different durations.
December 2024 in “PubMed” TrichoFoam™ effectively delivers multiple hair loss treatments, maintaining their stability and effectiveness.
Platelet-rich plasma (PRP) can help with hair loss and improve hair transplant results.
October 2022 in “Hair Transplantation” Dermoscopy helps identify hair loss types for better hair transplant evaluation.
May 2021 in “Journal of the Endocrine Society” Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.
January 2021 in “Figshare” Tiny lipid particles carrying 17-α-estradiol gather in hair follicles, which may help target alopecia treatment.
January 2020 in “Journal of the Brazilian Chemical Society” Tiny lipid particles loaded with a hormone gather in hair follicles, which may help treat hair loss.
June 2008 in “Experimental Dermatology” 17-beta estradiol and prednisolone may help regrow hair damaged by chemotherapy.
January 2006 in “Xibei zhiwu xuebao” Norethindrone and levonorgestrel can enhance or inhibit root growth in Arabidopsis thaliana depending on the concentration.
September 2002 in “Fertility and sterility” Metformin can start ovulation and may lower 17P response in PCOS, but six months is too short to improve hair growth or change body fat distribution.
February 1999 in “Analytical Sciences” A new antiandrogen compound was made and its detailed three-dimensional shape was described.
January 1983 in “Elsevier eBooks” Masculinization in affected individuals occurs gradually after puberty due to hormone changes.
December 2025 in “Biomolecules” Compound 7p shows strong potential as an anticancer agent.