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Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

Certain mutations in the hairless protein disrupt its ability to regulate the hair cycle.

Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.

Treat hirsutism in premenopausal women with oral contraceptives and consider additional treatments if needed.

ADAM17 could be a potential target for treating PCOS.

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.

Transamidases are present in the epidermis but their exact role is unclear.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Clascoterone is safe for the heart, even at high doses.

The method effectively identifies banned substances in hair loss and skin disease cosmetics.

The assay effectively detects hormonal activity of certain chemicals.

People with chronic Alopecia Areata often have lower vitamin D levels.

Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.

Both drugs lower DHT levels, with GI198745 being more effective.

A new method accurately measures long-term steroid levels in human hair.

Skin hormone levels change significantly after menopause.

A 77-year-old woman with hair loss had high testosterone and 17OH-progesterone levels, but no significant findings on imaging.

Low HDL-C, uric acid, and 25-hydroxyvitamin D are risk factors for early-onset male hair loss.

Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.

A new gene mutation causes vitamin D resistance and hair loss in two unrelated girls.