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Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.

Canine hair follicle cells metabolize DHEA and testosterone differently than human cells.

Routine genetic testing is crucial for early diagnosis and better management of Turner’s syndrome with 21-hydroxylase deficiency.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

A new method to make finasteride for hair loss treatment was developed.

The method can measure multiple hormones in women's hair and may help identify hormone-related health issues.

A new method accurately measures nine specific hormones in human blood.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Altering the keratin 17 gene in mice hair follicles caused temporary hair issues, but changes were minimal and short-lived.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

The enzymes Aldh1a2 and Aldh1a3 are involved in making retinoic acid in hair follicles and have different roles in hair growth.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

KRT17 may be a new target for endometrial cancer treatment because it helps cancer cells move and form new blood vessels.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Heart-specific steroid metabolism is crucial in cardiac hypertrophy.

Increasing type 17 collagen reduces aging signs in skin cells caused by UV light.

ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.

A specific enzyme that activates the hair growth medication minoxidil when applied to the skin was identified.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

ADAM17 could be a potential target for treating PCOS.

Keratin 17 is crucial for cell growth in wound healing by aiding protein synthesis.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

IL-17C is important in inflammatory skin diseases and could be a target for treatment.

5α-reductase enzyme affects hormone levels, influencing conditions like acne and hair loss.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

New compounds were made that effectively block a specific enzyme related to androgen conditions.