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The research found that androgens help control blood flow in the rat prostate through a specific binding site.

Many transgender men on testosterone therapy experience hair loss.

Finasteride was successfully synthesized from Pregnadienolone acetate.

A new compound may effectively inhibit the enzyme linked to BPH and hair loss.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

GT20029 showed some hair growth improvement, but longer studies are needed for better results.

Anabolic-androgenic steroids harm male hormone levels, sperm, metabolism, and can cause acne, hair loss, and breast growth.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

AH-001 could be a safer and more effective treatment for hair loss.

5α-reductase inhibitors can reduce prostate cancer risk but may increase high-grade tumors, needing more research.

Finasteride may reduce prostate cancer risk.

Testosterone increases seizure risk through its conversion to specific neurosteroids.

5ARI treatment improves PSA test accuracy for prostate cancer diagnosis.

Increased DHT formation in skin can cause hair loss, acne, and excessive hair growth, and antiandrogens might treat these conditions.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Higher free testosterone levels can increase bone density and decrease body fat but may raise the risk of prostate cancer, hair loss, and benign prostate enlargement.

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

The topical finasteride spray was safe and well-tolerated with stable effects.

Finasteride and dutasteride reduce semen quality, with dutasteride having a stronger negative effect.

Progesterone and its metabolites can prevent seizures without major side effects.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.