Search for 17b-estradiol in research

research Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate

2 citations , January 2011 in “Andrologia”

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

research Dihydrotestosterone induces p27 degradation via direct binding with SKP2 in ovarian and breast cancer

18 citations , April 2011 in “International Journal of Molecular Medicine”

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

research Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors

22 citations , June 2002 in “Journal of Medicinal Chemistry”

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Treatment of Androgenic Disorders with Dexamethasone: Dose-Response Relationship for Suppression of Dehydroepiandrosterone Sulfate

research Treatment of androgenic disorders with dexamethasone: Dose-response relationship for suppression of dehydroepiandrosterone sulfate

18 citations , January 1990 in “Journal of The American Academy of Dermatology”

Lower doses of dexamethasone can safely reduce high DHEAS levels in women with androgenic disorders.

research Effect of Evening Primrose Oil on Hyperandrogenism Markers in Women With Polycystic Ovarian Syndrome

September 2023 in “Research Square (Research Square)”

Evening primrose oil significantly improves hormone levels and reduces BMI and cholesterol in women with PCOS.

research Testosterone Treatment in Women – An Overview

8 citations , February 2009 in “Current Women's Health Reviews”

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Assessment of Diagnostic Competence of Plasmatic Androgens on Polycystic Ovary Syndrome Based on Receiver Operator Characteristic Curves

research Assessment of diagnostic competence of plasmatic androgens on polycystic ovary syndrome based on receiver operator characteristic curves

8 citations , March 2010 in “Gynecological Endocrinology”

Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.

research Diphenyl ethers as androgen receptor antagonists for the topical suppression of sebum production

7 citations , April 2009 in “Bioorganic & Medicinal Chemistry Letters”

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

research Effects of testosterone, dihydrotestosterone and estradiol on the growth behavior of cultured hair bulb papilla cells and root sheath fibroblasts

5 citations , January 1989

Testosterone and dihydrotestosterone slow hair cell growth, while estradiol has no effect.

research Steroid 5α-Reductase Inhibitors

42 citations , May 2003 in “Mini-reviews in Medicinal Chemistry”

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

research Insights From Liquid Chromatography-Mass Spectrometry-Measured Androgens in Indian Women With Polycystic Ovary Syndrome

January 2024 in “Curēus”

Androstenedione is better than testosterone for diagnosing PCOS in Indian women.

research Natural variability and the influence of concurrent control values on the detection and interpretation of low-dose or weak endocrine toxicities.

51 citations , February 2004 in “Environmental Health Perspectives”

Control variability makes it hard to confirm low-dose endocrine effects.