9 citations
,
January 2017 in “Organic Process Research & Development” In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
54 citations
,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
April 2016 in “Journal of Investigative Dermatology” FOL-005, a new substance, was found to reduce hair growth without toxicity when injected into skin, suggesting it could be used to treat excessive hair growth.
September 2019 in “Journal of Investigative Dermatology” PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.
1 citations
,
May 2001 in “Journal of Labelled Compounds and Radiopharmaceuticals” Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.
January 2014 in “cIRcle (University of British Columbia)” Photoacoustic imaging can detect prostate brachytherapy seeds better with enhanced contrast methods, but depth limits remain.
2 citations
,
September 1992 in “Steroids” New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
13 citations
,
July 2016 in “BMC Complementary and Alternative Medicine” Hominis Placenta helps hair grow back by increasing cell growth and a specific growth factor.
1 citations
,
January 2012 in “Analytical chemistry, an Indian journal” A reliable method was developed to accurately measure tamsulosin hydrochloride and finasteride in tablets.
4 citations
,
May 2024 in “Steroids” The method accurately measures sex hormones in human plasma but can have small errors.
12 citations
,
June 2011 in “Journal of applied polymer science” L-phenylalanine and hydrolyzed eggwhite protein deeply penetrate human hair.
January 2004 in “Zhōnghuá yàoxué zázhì” The new method for making finasteride is cheaper and gives a higher yield.
April 2019 in “Journal of the Endocrine Society” Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.
11 citations
,
September 2020 in “Steroids” A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.
12 citations
,
February 2023 in “Applied and Environmental Microbiology” Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.
4 citations
,
May 2024 in “Rapid Communications in Mass Spectrometry” Girard's reagent P improves detection of spironolactone and its metabolites.
54 citations
,
May 1994 in “Veterinary Pathology” PTHrP is higher in certain dog tumors and may act as a local growth factor.
5 citations
,
October 2018 in “Journal of Clinical Laboratory Analysis” Women with PCOS who have high male hormone levels often also have insulin resistance.
October 2011 in “The American Journal of Gastroenterology” Esomeprazole can cause hepatitis.
January 2003 in “Pharmaceutical Journal of Chinese People's Liberation Army” The method accurately measures finasteride tablet dissolution.
45 citations
,
June 2008 in “Journal of pharmaceutical and biomedical analysis” The method effectively identifies banned substances in hair loss and skin disease cosmetics.
January 2009 in “Xiandai huagong” Finasteride was successfully synthesized from Pregnadienolone acetate.
January 2011 in “Zhongguo xin yao zazhi” A new, safer method to make finasteride from progesterone is effective for industrial use.
October 2013 in “Handbook of Metabolic Pathways of Xenobiotics” Finasteride is mostly broken down in the body and excreted in urine and feces.
January 1995 in “대한피부과학회지” Higher hormone levels may be linked to female hair loss.
10 citations
,
August 2013 in “Experimental Dermatology” Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
January 2020 in “International Journal of Research in Pharmacy and Chemistry” A reliable method was created to measure dutasteride and related molecules in capsules.
5 citations
,
July 2021 in “Endocrinology, diabetes & metabolism” Glioblastoma cells can make androgens, which might help the tumor grow.
27 citations
,
May 2002 in “The Journal of Clinical Endocrinology & Metabolism” Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.