Search

everythinglearnresearchcommunity

for

Search:↓

Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Human hair follicles can process steroid hormones like DHEA.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

A new compound was made that might help treat diseases related to male hormones.

A single amino acid change in the vitamin D receptor can disrupt its function and lead to hair loss.

New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.

A new mutation in the HJV gene was found in a young woman with juvenile hemochromatosis, causing unusual symptoms like secondary hypothyroidism.

The study concluded that androstendione and DHEA are important for diagnosing high male hormone levels in women with excessive hair growth.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

A new gene mutation causes vitamin D resistance and hair loss in two unrelated girls.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Higher DHEA-S levels are linked to smaller ovarian volume in women with PCOS.

5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

VDDR I and II are genetic disorders affecting vitamin D use, causing rickets, with VDDR I treatable by vitamin D supplements and VDDR II needing high doses and calcium.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.