77 citations
,
March 2004 in “Human Reproduction” Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.
11 citations
,
February 1982 in “Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis” A new method can detect mutations in mice by observing changes in hair follicle cells.
June 2025 in “Molecular Therapy — Nucleic Acids” A new treatment using a DNA aptamer can promote hair growth by targeting a specific receptor.
April 2018 in “Journal of Investigative Dermatology” Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.
81 citations
,
February 2000 in “Anti-cancer drugs” Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
A method was created to measure oxymatrine in human blood.
8 citations
,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
9 citations
,
October 2013 in “Journal of Investigative Dermatology” The OVOL1 gene, controlled by β-catenin, is crucial for creating hair follicles.
17 citations
,
September 1953 in “Journal of Cell Science” INT effectively shows enzyme activity and protein groups in wool and hair follicles.
October 2025 in “Journal of the Endocrine Society” Ovarian hyperthecosis can cause high testosterone and symptoms like hair loss, and surgery can help improve these symptoms.
111 citations
,
April 2006 in “Annals of the New York Academy of Sciences” Vitamin D receptor is essential for healthy bones and skin.
50 citations
,
October 2011 in “Archives of Biochemistry and Biophysics” Vitamin D receptor is essential for healthy hair growth.
42 citations
,
December 2015 in “International Journal of Clinical Pharmacology and Therapeutics” The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.
January 2010 in “Life Science Alliance” Vitamin D receptor is essential for preventing hair loss by regulating hair cycle stages.
A reliable method was developed to ensure hair growth products have the right amount of active ingredients.
March 2019 in “Evidence Based Women Health Journal (Online)” Vitamin D supplements increased ovulation rates in women with PCOS who were vitamin D deficient.
January 2021 in “Medical Research Archives” Genetically modified rats help reveal how vitamin D affects bone and skin health.
76 citations
,
September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
A new genetic mutation was found causing hair and eye issues in a boy.
24 citations
,
February 2007 in “Hormone and metabolic research” The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
28 citations
,
March 1973 in “The Journal of Clinical Endocrinology & Metabolism” Altered DHEA metabolism in hair follicles may be linked to hair loss in balding men.
17 citations
,
October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
Finasteride harms Daphnia magna's reproduction and metabolism.
22 citations
,
January 2001 in “Chemical & Pharmaceutical Bulletin” Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
18 citations
,
October 2017 in “Drug Design Development and Therapy” DA-9401 helps protect rat testis from finasteride damage.
1 citations
,
January 2017 in “Tohoku journal of experimental medicine” A woman's mature cystic teratoma caused her virilization by producing testosterone.
71 citations
,
May 1996 in “Journal of Investigative Dermatology” Ornithine decarboxylase is crucial for hair growth regulation in mice.
21 citations
,
September 1977 in “Journal of Pharmaceutical Sciences” Minoxidil levels measured in human blood.