21 citations
,
November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
8 citations
,
June 1995 in “Helvetica Chimica Acta” Compound 15a was effective in inhibiting 5α-reductase.
8 citations
,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
7 citations
,
November 2022 in “Communications biology” Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
2 citations
,
January 2020 in “BioMed Research International” Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
January 2025 in “Cellular & Molecular Biology Letters” Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
October 2023 in “International journal of rheumatic diseases” New treatments targeting the JAK signaling pathway, especially JAK inhibitors, show promise for alopecia areata.
343 citations
,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
286 citations
,
January 2009 in “Human Reproduction Update” Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.
162 citations
,
January 2015 in “Trends in Endocrinology and Metabolism” Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.
88 citations
,
April 2011 in “Archives of Dermatology” Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.
52 citations
,
November 2009 in “International journal of gynaecology and obstetrics” High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.
48 citations
,
July 1993 in “Archives of Dermatological Research” Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.
39 citations
,
February 2011 in “The Prostate/The prostate” Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.
34 citations
,
January 2022 in “Frontiers in Immunology” IL-25 helps heal diabetic wounds by improving blood vessel and skin cell functions.
34 citations
,
January 2014 in “Indian Dermatology Online Journal” Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.
32 citations
,
April 2014 in “American Journal of Clinical Dermatology” People with psoriasis are more likely to have Metabolic Syndrome than those without psoriasis.
29 citations
,
October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
28 citations
,
November 2014 in “Current Diabetes Reports” Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.
25 citations
,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
25 citations
,
July 1994 in “Archives of Dermatology” A man's skin condition, pemphigus vulgaris, came back after he was treated with interleukin 2 for cancer.
20 citations
,
December 2013 in “PubMed” Quercetin boosts melanin production in mouse hair follicles.
19 citations
,
October 2012 in “Frontiers of Hormone Research” Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.
18 citations
,
March 2014 in “Current Pharmaceutical Biotechnology” Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
16 citations
,
March 2011 in “Pediatric diabetes” Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
14 citations
,
September 2017 in “Clinics in Dermatology” Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.
13 citations
,
August 2016 in “Medical Hypotheses” Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.
13 citations
,
May 2016 in “International journal of biological macromolecules” Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
Many women with postadolescent acne also have hormonal imbalances and are at higher risk for metabolic issues.
February 2020 in “Spiral (Imperial College London)” Duodenal mucosal resurfacing did not improve insulin sensitivity or reproductive function in women with PCOS.