February 2023 in “International Journal of Medical Arts” Trichloroacetic acid is a safe and effective treatment for hair loss in alopecia areata patients.
August 2021 in “Josai University Repository of Academia (Josai University)” The nanoparticles improved minoxidil's skin absorption, making them promising for skin treatments.
March 2014 in “Institutional Repositories DataBase (IRDB)” Skin-derived stem cells could help treat skin aging and pigmentation issues.
73 citations
,
March 2017 in “Scientific Reports” Bioengineered tooth germ can restore whole teeth in dogs.
23 citations
,
January 2024 in “Nature Immunology” γδ T cells adapt uniquely to different tissues in mice.
4 citations
,
December 2020 in “Journal of Dermatology” Impaired autophagy may cause hair loss by triggering early catagen.
1057 citations
,
November 2011 in “Annals of Biomedical Engineering” Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
520 citations
,
February 2001 in “Journal of Clinical Investigation” VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
260 citations
,
July 2010 in “Cell” Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
248 citations
,
December 2011 in “Journal of Neuroscience” Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
248 citations
,
November 2011 in “The EMBO Journal” Wnt1/βcatenin signaling is crucial for heart repair after injury.
201 citations
,
November 1964 in “Journal of neurophysiology” The cuneate nucleus has two main neuron types: relay neurons and interneurons.
184 citations
,
December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
165 citations
,
October 2013 in “Nature Communications” Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
165 citations
,
September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
150 citations
,
August 1992 in “Genes & Development” TNF alpha in skin cells causes weight loss, hair and fat issues, and skin inflammation in mice.
136 citations
,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
96 citations
,
September 2017 in “Analytica Chimica Acta” Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.
87 citations
,
September 2019 in “Nature Communications” SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.
86 citations
,
June 2017 in “Stem cell investigation” Stem cells from hair follicles can safely treat hair loss.
86 citations
,
April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
85 citations
,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
84 citations
,
April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
82 citations
,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
77 citations
,
April 2016 in “Science Advances” Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
76 citations
,
May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
75 citations
,
November 2016 in “Medicines” Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
65 citations
,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
56 citations
,
March 2016 in “International Wound Journal” Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.